Item Type | Name |
Concept
|
Acylation
|
Concept
|
Age Factors
|
Concept
|
Acetylation
|
Concept
|
Angiotensin II
|
Concept
|
Aortic Valve Stenosis
|
Concept
|
Aftercare
|
Concept
|
Acridines
|
Concept
|
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
|
Concept
|
Aminorex
|
Concept
|
Ambulatory Care
|
Concept
|
Bundle-Branch Block
|
Concept
|
Carbazoles
|
Concept
|
Chlorides
|
Concept
|
Antihypertensive Agents
|
Concept
|
Antioxidants
|
Concept
|
Cyclohexanols
|
Concept
|
Appetite Depressants
|
Concept
|
Benzamides
|
Concept
|
Benzoates
|
Concept
|
Dichloroacetic Acid
|
Concept
|
Digoxin
|
Concept
|
Dimercaprol
|
Concept
|
Dithionitrobenzoic Acid
|
Concept
|
Body Weight
|
Concept
|
Cardiology
|
Concept
|
Citric Acid Cycle
|
Concept
|
Chicago
|
Concept
|
Bradykinin
|
Concept
|
Classification
|
Concept
|
Cardiotonic Agents
|
Concept
|
Cytosol
|
Concept
|
Diabetes Mellitus, Type 2
|
Concept
|
Culture Media
|
Concept
|
Iliac Vein
|
Concept
|
Diet Surveys
|
Concept
|
Dithionite
|
Concept
|
Cyanides
|
Concept
|
Cytochrome c Group
|
Concept
|
Cytoplasm
|
Concept
|
Drug Synergism
|
Concept
|
Immunosuppressive Agents
|
Concept
|
Injections, Intramuscular
|
Concept
|
Iron
|
Concept
|
Endarterectomy
|
Concept
|
Endothelium, Vascular
|
Concept
|
Cytochrome P-450 Enzyme System
|
Concept
|
Disulfides
|
Concept
|
Cause of Death
|
Concept
|
Child, Preschool
|
Concept
|
Ductus Arteriosus, Patent
|
Concept
|
Fluoresceins
|
Concept
|
Health Surveys
|
Concept
|
Long QT Syndrome
|
Concept
|
Clitoris
|
Concept
|
Mass Screening
|
Concept
|
Cross-Sectional Studies
|
Concept
|
Electron Transport Complex IV
|
Concept
|
DNA
|
Concept
|
Dobutamine
|
Concept
|
Double-Blind Method
|
Concept
|
Fishes
|
Concept
|
Ferrous Compounds
|
Concept
|
Indicators and Reagents
|
Concept
|
Indoles
|
Concept
|
Electrocardiography
|
Concept
|
Microtubule-Associated Proteins
|
Concept
|
Atrial Natriuretic Factor
|
Concept
|
Genes, Dominant
|
Concept
|
Fasting
|
Concept
|
Feasibility Studies
|
Concept
|
Ferric Compounds
|
Concept
|
Forced Expiratory Volume
|
Concept
|
Dietary Fats, Unsaturated
|
Concept
|
Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
|
Concept
|
Cyclic GMP
|
Concept
|
Health Education
|
Concept
|
Hydrogen Peroxide
|
Concept
|
Hyperlipoproteinemia Type II
|
Concept
|
Hypoglycemic Agents
|
Concept
|
Liposomes
|
Concept
|
Hospitalization
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Gastroesophageal Reflux
|
Concept
|
Glutathione
|
Concept
|
Guanylate Cyclase
|
Concept
|
Headache
|
Concept
|
Lipoma
|
Concept
|
Iron-Sulfur Proteins
|
Concept
|
Metformin
|
Concept
|
Hydrazines
|
Concept
|
Mitral Valve Stenosis
|
Concept
|
Phentermine
|
Concept
|
Phosphatidylcholines
|
Concept
|
Pilot Projects
|
Concept
|
Nitrates
|
Concept
|
Platelet-Derived Growth Factor
|
Concept
|
Meclofenamic Acid
|
Concept
|
Immunohistochemistry
|
Concept
|
Organ Culture Techniques
|
Concept
|
Organ Size
|
Concept
|
Muscle, Smooth, Vascular
|
Concept
|
Neomycin
|
Concept
|
Glycolysis
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Random Allocation
|
Concept
|
Muscle Tonus
|
Concept
|
Myocardial Contraction
|
Concept
|
Health Policy
|
Concept
|
HeLa Cells
|
Concept
|
Herpes Simplex
|
Concept
|
Pergolide
|
Concept
|
Ion Channels
|
Concept
|
Neutrophils
|
Concept
|
Phagocytosis
|
Concept
|
Ligands
|
Concept
|
Cholesterol, HDL
|
Concept
|
Mitochondria, Heart
|
Concept
|
Persistent Fetal Circulation Syndrome
|
Concept
|
Phthalimides
|
Concept
|
Phenylurea Compounds
|
Concept
|
Physical Conditioning, Animal
|
Concept
|
Nitrites
|
Concept
|
Porphyrins
|
Concept
|
Phycoerythrin
|
Concept
|
Drug Prescriptions
|
Concept
|
Propionates
|
Concept
|
Epoprostenol
|
Concept
|
Thymoma
|
Concept
|
Prostaglandins
|
Concept
|
Pulmonary Alveoli
|
Concept
|
Triterpenes
|
Concept
|
Glomerular Mesangium
|
Concept
|
Glutamine
|
Concept
|
Heart Defects, Congenital
|
Concept
|
Referral and Consultation
|
Concept
|
Registries
|
Concept
|
Research Support as Topic
|
Concept
|
Restaurants
|
Concept
|
Risk Factors
|
Concept
|
Quality of Life
|
Concept
|
Wolff-Parkinson-White Syndrome
|
Concept
|
Xanthine Oxidase
|
Concept
|
Somatostatin
|
Concept
|
Rotenone
|
Concept
|
Potassium Channels
|
Concept
|
Cohort Studies
|
Concept
|
Radioisotopes
|
Concept
|
Interleukin-6
|
Concept
|
Serotonin
|
Concept
|
Health Knowledge, Attitudes, Practice
|
Concept
|
Rest
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Histones
|
Concept
|
Homeostasis
|
Concept
|
House Calls
|
Concept
|
Humans
|
Concept
|
Hypercholesterolemia
|
Concept
|
Incidence
|
Concept
|
Linear Models
|
Concept
|
Single-Blind Method
|
Concept
|
Superoxides
|
Concept
|
Training Support
|
Concept
|
Intracellular Membranes
|
Concept
|
CHO Cells
|
Concept
|
Cardiology Service, Hospital
|
Concept
|
Hypertrophy, Right Ventricular
|
Concept
|
Waiting Lists
|
Concept
|
Warfarin
|
Concept
|
Vasodilator Agents
|
Concept
|
3',5'-Cyclic-GMP Phosphodiesterases
|
Concept
|
Drug Design
|
Concept
|
Calcium Channels
|
Concept
|
Sex Distribution
|
Concept
|
Lung
|
Concept
|
Randomized Controlled Trials as Topic
|
Concept
|
Risk Assessment
|
Concept
|
Cell Culture Techniques
|
Concept
|
Radiopharmaceuticals
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
rhoB GTP-Binding Protein
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Guanosine 5'-O-(3-Thiotriphosphate)
|
Concept
|
4-Aminopyridine
|
Concept
|
Prevalence
|
Concept
|
Exercise
|
Concept
|
Fatty Acids, Omega-3
|
Concept
|
Ion Channel Gating
|
Concept
|
Mitochondria
|
Concept
|
Mitochondria, Muscle
|
Concept
|
Lung Transplantation
|
Concept
|
Comorbidity
|
Concept
|
N-Acetylgalactosaminyltransferases
|
Concept
|
Muscle Contraction
|
Concept
|
Case-Control Studies
|
Concept
|
Age Distribution
|
Concept
|
Time Management
|
Concept
|
Genes, Reporter
|
Concept
|
Microtubules
|
Concept
|
NADH Dehydrogenase
|
Concept
|
National Institutes of Health (U.S.)
|
Concept
|
Cyclooxygenase Inhibitors
|
Concept
|
Mice, Knockout
|
Concept
|
Efficiency, Organizational
|
Concept
|
Cell Proliferation
|
Concept
|
Impotence, Vasculogenic
|
Concept
|
Telomerase
|
Concept
|
Cytochrome P-450 CYP2E1
|
Concept
|
Inhibitor of Apoptosis Proteins
|
Concept
|
Glucose Intolerance
|
Concept
|
Simvastatin
|
Concept
|
Dietary Sucrose
|
Concept
|
Bone Morphogenetic Protein Receptors, Type II
|
Concept
|
Natriuretic Peptide, Brain
|
Concept
|
Metabolic Syndrome
|
Concept
|
Feedback, Physiological
|
Concept
|
Potassium Channel Blockers
|
Concept
|
Romano-Ward Syndrome
|
Concept
|
Cross-Over Studies
|
Concept
|
SOXF Transcription Factors
|
Concept
|
GTP Phosphohydrolases
|
Concept
|
Receptors, Dopamine D1
|
Concept
|
Sirtuin 3
|
Concept
|
Fatal Outcome
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
Concept
|
MAP Kinase Kinase 4
|
Concept
|
Chloride Channels
|
Concept
|
Endothelin-1
|
Concept
|
Hydroxylamine
|
Concept
|
Ryanodine Receptor Calcium Release Channel
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
Concept
|
5' Untranslated Regions
|
Concept
|
Opioid Peptides
|
Concept
|
3' Untranslated Regions
|
Concept
|
rhoA GTP-Binding Protein
|
Concept
|
DNA, Intergenic
|
Concept
|
Nuclear Pore
|
Concept
|
Potassium Channels, Inwardly Rectifying
|
Concept
|
Evidence-Based Medicine
|
Concept
|
Mitochondrial Diseases
|
Concept
|
Phenyl Ethers
|
Concept
|
Prostaglandins F
|
Concept
|
Prostaglandins, Synthetic
|
Concept
|
Rats, Inbred Strains
|
Concept
|
Severity of Illness Index
|
Concept
|
RNA, Messenger
|
Concept
|
Schools, Medical
|
Concept
|
Substance P
|
Concept
|
Electron Transport Complex I
|
Concept
|
Sulfhydryl Reagents
|
Concept
|
Dioxygenases
|
Concept
|
Cytokine Receptor gp130
|
Concept
|
Culture Techniques
|
Concept
|
Staphylococcus aureus
|
Concept
|
Stereoisomerism
|
Concept
|
Dyslipidemias
|
Concept
|
Xanthomatosis
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
STAT2 Transcription Factor
|
Concept
|
HIV Infections
|
Concept
|
Delayed Rectifier Potassium Channels
|
Concept
|
Logistic Models
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Thyroid Neoplasms
|
Concept
|
von Willebrand Diseases
|
Concept
|
Blotting, Northern
|
Concept
|
Reproducibility of Results
|
Concept
|
Patient Satisfaction
|
Concept
|
Genetic Therapy
|
Concept
|
HLA-DP alpha-Chains
|
Concept
|
Ion-Selective Electrodes
|
Concept
|
Survival Rate
|
Concept
|
Hypoplastic Left Heart Syndrome
|
Concept
|
Cellular Senescence
|
Concept
|
Exercise Tolerance
|
Concept
|
Telemedicine
|
Concept
|
Metabolic Networks and Pathways
|
Concept
|
Dietary Supplements
|
Concept
|
Dexfenfluramine
|
Concept
|
Gadolinium DTPA
|
Concept
|
Cation Transport Proteins
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
History, 20th Century
|
Concept
|
E2F1 Transcription Factor
|
Concept
|
Kv Channel-Interacting Proteins
|
Concept
|
Shal Potassium Channels
|
Concept
|
Pulmonary Disease, Chronic Obstructive
|
Concept
|
Genome-Wide Association Study
|
Concept
|
AMP-Activated Protein Kinases
|
Concept
|
Secondary Prevention
|
Concept
|
Dynamins
|
Concept
|
RNA, Small Interfering
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Endothelial Cells
|
Concept
|
Cytochromes c
|
Concept
|
Premature Birth
|
Concept
|
Nicotinamide Phosphoribosyltransferase
|
Concept
|
rho-Associated Kinases
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 5
|
Concept
|
Growth Differentiation Factor 2
|
Concept
|
Drug Discovery
|
Concept
|
Cyclin B1
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Benzenesulfonates
|
Concept
|
Calcium Channel Blockers
|
Concept
|
Cardiovascular Agents
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Cyanamide
|
Concept
|
Diabetes Mellitus
|
Concept
|
Diastole
|
Concept
|
Electron Transport
|
Concept
|
Epinephrine
|
Concept
|
Physical Exertion
|
Concept
|
Fenfluramine
|
Concept
|
Fibrinolytic Agents
|
Concept
|
Follow-Up Studies
|
Concept
|
Food Preferences
|
Concept
|
Genetic Counseling
|
Concept
|
Glucose
|
Concept
|
Guanosine Diphosphate
|
Concept
|
Erectile Dysfunction
|
Concept
|
Longitudinal Studies
|
Concept
|
Lymphocytes
|
Concept
|
Muscle Relaxation
|
Concept
|
Norepinephrine
|
Concept
|
Panic
|
Concept
|
Predictive Value of Tests
|
Concept
|
Prospective Studies
|
Concept
|
Respiration, Artificial
|
Concept
|
Retrospective Studies
|
Concept
|
Sincalide
|
Concept
|
Systole
|
Concept
|
Thermodilution
|
Concept
|
Vitamin A
|
Concept
|
Hypertriglyceridemia
|
Concept
|
Dinoprost
|
Concept
|
Cytokines
|
Concept
|
Databases, Factual
|
Concept
|
Iloprost
|
Concept
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
Concept
|
Nitric Oxide Donors
|
Concept
|
Calcium Channels, L-Type
|
Concept
|
Potassium Channels, Voltage-Gated
|
Concept
|
Potassium Channels, Calcium-Activated
|
Concept
|
Optic Atrophy, Autosomal Dominant
|
Concept
|
Mitochondrial Membrane Transport Proteins
|
Concept
|
MicroRNAs
|
Concept
|
Tissue Culture Techniques
|
Concept
|
Microscopy, Electron, Transmission
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channels
|
Concept
|
Kv1.5 Potassium Channel
|
Concept
|
Shab Potassium Channels
|
Concept
|
Atrioventricular Block
|
Concept
|
G-Protein-Coupled Receptor Kinase 2
|
Concept
|
HLA-DP beta-Chains
|
Academic Article
|
Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue.
|
Academic Article
|
Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
|
Academic Article
|
Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel.
|
Academic Article
|
Diversity of response in vascular smooth muscle cells to changes in oxygen tension.
|
Academic Article
|
Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
|
Academic Article
|
Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
|
Academic Article
|
Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity.
|
Academic Article
|
Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing.
|
Academic Article
|
The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
|
Academic Article
|
Ion channels in the pulmonary vasculature.
|
Academic Article
|
Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs.
|
Academic Article
|
Potassium channel diversity in vascular smooth muscle cells.
|
Academic Article
|
Utility of a nitric oxide electrode for monitoring the administration of nitric oxide in biologic systems.
|
Academic Article
|
Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology.
|
Academic Article
|
Alterations in a redox oxygen sensing mechanism in chronic hypoxia.
|
Academic Article
|
Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
|
Academic Article
|
Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
|
Academic Article
|
A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent.
|
Academic Article
|
Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
|
Academic Article
|
Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction.
|
Academic Article
|
Redox control of oxygen sensing in the rabbit ductus arteriosus.
|
Academic Article
|
GTP (gammaS) and GDP (betaS) as electron donors: new wine in old bottles.
|
Academic Article
|
Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
|
Academic Article
|
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
|
Academic Article
|
Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
|
Academic Article
|
Triple-bonded unsaturated fatty acids are redox active compounds.
|
Academic Article
|
Voltage-gated potassium channels in human ductus arteriosus.
|
Academic Article
|
Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
|
Academic Article
|
The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies.
|
Academic Article
|
Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels.
|
Academic Article
|
In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
|
Academic Article
|
Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
|
Academic Article
|
Innovative strategic Canadian research training from TomorrOw's Research Cardiovascular Health Care Professionals (TORCH).
|
Academic Article
|
Cellular and molecular pathobiology of pulmonary arterial hypertension.
|
Academic Article
|
Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide.
|
Academic Article
|
Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.
|
Academic Article
|
The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.
|
Academic Article
|
Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
|
Academic Article
|
Acute oxygen-sensing mechanisms.
|
Academic Article
|
Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling.
|
Academic Article
|
The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
|
Academic Article
|
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
|
Academic Article
|
The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
|
Academic Article
|
Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
|
Academic Article
|
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
|
Academic Article
|
Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
|
Academic Article
|
O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
|
Academic Article
|
Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
|
Academic Article
|
Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
|
Academic Article
|
Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
|
Academic Article
|
The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
|
Academic Article
|
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
|
Academic Article
|
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.
|
Academic Article
|
Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
|
Academic Article
|
The association between erectile dysfunction and peripheral arterial disease as determined by screening ankle-brachial index testing.
|
Academic Article
|
Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
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Academic Article
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Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
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Academic Article
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Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth?
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Academic Article
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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
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Academic Article
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Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease.
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Academic Article
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Academic Article
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Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.
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Academic Article
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The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
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Academic Article
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A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward).
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Academic Article
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Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
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Academic Article
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Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
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Academic Article
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Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.
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Academic Article
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Redox status in the control of pulmonary vascular tone.
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Academic Article
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Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
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Academic Article
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Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
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Academic Article
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Diversity of phenotype and function of vascular smooth muscle cells.
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Academic Article
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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
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Academic Article
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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Academic Article
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A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension.
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Academic Article
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Potassium channels regulate tone in rat pulmonary veins.
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Academic Article
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Diversity in mitochondrial function explains differences in vascular oxygen sensing.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.
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Academic Article
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Hypoxic pulmonary vasoconstriction.
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Academic Article
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
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Academic Article
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A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.
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Academic Article
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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
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Academic Article
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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Academic Article
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Relationship between changes in dietary sucrose and high density lipoprotein cholesterol: the CARDIA study. Coronary Artery Risk Development in Young Adults.
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Academic Article
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Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model.
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Academic Article
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Noninvasive cardiac output measurements in patients with pulmonary hypertension.
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Academic Article
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Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
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Academic Article
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Rodent models of group 1 pulmonary hypertension.
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Academic Article
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Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.
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Academic Article
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Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension.
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Academic Article
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[Relevant issues in the pathology and pathobiology of pulmonary hypertension].
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Academic Article
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Right ventricular adaptation and failure in pulmonary arterial hypertension.
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Academic Article
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Mitochondrial dynamics in pulmonary arterial hypertension.
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Academic Article
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Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.
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Academic Article
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A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.
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Academic Article
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Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
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Academic Article
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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Academic Article
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Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
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Academic Article
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Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement.
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Academic Article
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PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
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Academic Article
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Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.
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Academic Article
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Mitochondria in human neutrophils mediate killing of Staphylococcus aureus.
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Academic Article
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The comprehensive transcriptome of human ductus arteriosus smooth muscle cells (hDASMC).
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Concept
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Imatinib Mesylate
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Concept
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Venlafaxine Hydrochloride
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Concept
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Health Equity
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Concept
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A549 Cells
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Concept
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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
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Concept
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Soluble Guanylyl Cyclase
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Concept
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RNA, Long Noncoding
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Concept
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Familial Primary Pulmonary Hypertension
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Concept
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In Vitro Techniques
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Concept
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ErbB Receptors
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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Academic Article
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Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response.
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Academic Article
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Multi-omic and multispecies analysis of right ventricular dysfunction.
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Academic Article
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Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions.
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